Can keratocystic odontogenic tumor recur?
Last Update: April 20, 2022
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The Keratocystic Odontogenic Tumor (KCOT) is characterized by its high tendency to recur after surgical treatment. This is attributed to its infiltrative growth pattern and to the failure during surgery to remove the epithelial rests of the dental lamina or the daughter cysts [1-4].
Which odontogenic tumor has the highest recurrence rate?
In our series, the sites of OKC were not statistically related to recurrence. However, the posterior mandibular or maxillary regions were the most high-risk location for recurrence.
Why do odontogenic Keratocysts recur?
OKC is known for its rapid growth and its tendency to invade the adjacent tissues including bone. It has a high recurrence rate of 16 to 30%. Odontogenic keratocysts are generally thought to be derived from either the epithelial remnants of the tooth germ or the basal cell layer of the surface epithelium.
What causes Keratocystic odontogenic tumors?
Contributing causes include thin and fragile epithelium leading to incomplete removal, cyst extensions extending into cancellous bone, satellite cysts found in the wall, experience of the surgeon, formation of further new cysts from other remnants of the dental epithelium.
Why is OKC recurrence rate so high?
There are several possible reasons why OKC recur so frequently and require meticulous surgical planning and execution. The first of these is related to their tendency to multiplicity in some patients, including the occurrence of satellite cysts, which may be retained during an enucleation procedure.
Treating and Avoiding Recurrence of Keratocystic Odontogenic Tumors (KCOTS)
Which cyst has highest recurrence rate?
Odontogenic Keratocyst (Keratocystic Odontogenic Tumor) The odontogenic keratocyst is a distinct clinicopathologic entity with a clearly identifiable histologic appearance. Clinically it is characterized by a high rate of recurrence after treatment and by the potential to become an aggressive, bone-destructive lesion.
Which is the most common odontogenic cyst?
Dentigerous cysts are the most common of odontogenic cysts and can occur at any tooth location, but most often occur in third molars and maxillary canines, locations most often involved in tooth impaction.
Is Odontogenic Keratocyst a tumor?
The odontogenic keratocyst (OKC, currently designated by the World Health Organization as a keratocystic odontogenic tumor) is a locally aggressive, cystic jaw lesion with a putative high growth potential and a propensity for recurrence.
Is Odontogenic Keratocyst cancerous?
odontogenic keratocyst (OKC) is considered a benign cyst that can assume a locally aggressive and destructive behavior. Atypia of its lining is uncom- mon, and frank malignant degeneration is rare. Presence of these changes may remain clinically undetected and carry a significant influence on treatment and outcome.
Is Odontogenic Keratocyst painful?
Clinical Features and Imaging
Clinically, odontogenic keratocysts (OKCs) generally present as a swelling, with or without pain.
Do Dentigerous cysts recur?
Dentigerous cyst (DC) is one of the most common odontogenic cysts of the jaws and rarely recurs.
What is odontogenic Keratocyst?
Odontogenic keratocyst (OKC) is the cyst arising from the cell rests of dental lamina. It can occur anywhere in the jaw, but commonly seen in the posterior part of the mandible. Radiographically, most OKCs are unilocular when presented at the periapex and can be mistaken for radicular or lateral periodontal cyst.
What is Carnoy's solution used for?
Carnoy's solution is a substance used as a complementary treatment after the conservative excision of odontogenic keratocyst. The application of Carnoy's solution promotes a superficial chemical necrosis and is intended to reduce recurrence rates.
Why does Ameloblastoma recur?
It is known that survival rates decline with increased age at initial diagnosis. In addition, poor prognosis in these situations is in large part due to the microscopic infiltration of tumor cells into neighboring healthy brain tissue, thereby limiting the extent of resection, thus increasing the recurrence rate.
What does odontogenic mean?
1 : forming or capable of forming teeth odontogenic tissues. 2 : containing or arising from odontogenic tissues odontogenic tumors.
Can Ameloblastoma come back?
The overall recurrence rate of ameloblastoma with current methods of treatment is approximately 10% (7), and recurrent cases are malignant (11). This result is relatively high for a benign tumor.
What percentage of dental cysts are cancerous?
The incidence of carcinomas, either squamous or mucoepidermoid, originating from odontogenic cysts represents less than 1% (5,19). According to Muller and Waldron (34), 70% of primary intraosseous carcinomas develop from pre-existing cysts and these account for 1 to 2% of overall oral cancers (15,42,43).
How do you know if you have a tumor in your jaw?
A tumor could cause tooth mobility on your jawbone, pushing your teeth out of place. While pain, swelling, lumps on the jaw, or loose teeth could be due to other oral conditions, they're also all realistic jaw cancer symptoms.
Can a cyst in the jaw be cancerous?
Jaw cysts are generally benign in nature and non-cancerous growths, but may present with malignant degeneration very rarely. Cystic jaw lesions tend to grow very slowly and in many patients, they are asymptomatic (i.e. they do not cause any noticeable symptoms).
How is odontogenic Keratocyst treated?
Multiple surgical approaches were introduced including decompression, marsupilization, enucleation with or without adjunct (Carnoy's solution, cryotherapy), and resection. Depending on other studies KCOT can be conservatively treated with enculation and application of Carnoy's solution or cryotherapy.
How can odontogenic cysts appear on radiographs?
At radiography, an odontogenic keratocyst usually appears as a unilocular, lucent lesion with smooth, corticated borders that is often associated with an impacted tooth (,,,Fig 5).
What are odontogenic tumors?
Odontogenic tumor is the medical term for a growth or cyst that affects the jaw. They range greatly in size and severity and most are benign (non-cancerous; non-spreading). In rare cases they may be cancerous (malignant) and may spread.
How common are odontogenic cyst?
The most frequent odontogenic cyst was radicular (54.7%), followed by dentigerous (26.6%), residual (13.7%), odontogenic keratocyst (3.3%), and lateral periodontal cyst (0.2%). Nasopalatine duct cyst (1.5%) was the only nonodontogenic cyst. By age, cysts peaked in the third decade (24.2%).
Which is the most common non odontogenic cyst?
The nonodontogenic cysts of the jaws that are most often encountered are the central giant cell granuloma, traumatic bone cavity, aneurysmal bone cyst, nasopalatine duct cyst, and nasolabial cyst.
What is the difference between odontogenic and Nonodontogenic cyst?
Odontogenic cysts arise from remnants of the odontogenic epithelium entrapped in bone or gingival tissue, while non-odontogenic cysts develop from epithelium of non-odontogenic origin.