Is fluorouracil cream dangerous?

Last Update: April 20, 2022

This is a question our experts keep getting from time to time. Now, we have got the complete detailed explanation and answer for everyone, who is interested!

Asked by: Maye Cole Sr.
Score: 4.8/5 (46 votes)

Many people using this medication do not have serious side effects. Tell your doctor right away if any of these rare but very serious side effects occur: stomach/abdominal pain, bloody diarrhea, vomiting, signs of infection (e.g., fever, chills, persistent sore throat), easy bruising/bleeding, mouth sores.

How long does it take for skin to heal after fluorouracil?

Complete healing of the inflammation generally takes one to two months. In addition to treating clinically visible lesions, fluorouracil can also treat subclinical lesions6 that may have become clinically visible in the future.

Can fluorouracil make you sick?

The following side effects are common (occurring in greater than 30%) for patients taking Fluorouracil: Diarrhea. Nausea and possible occasional vomiting. Mouth sores.

Does fluorouracil cream affect healthy skin?

This is a pre-cancerous skin growth caused by the sun. Fluorouracil reacts against the pre-cancerous sun-damaged skin but does not usually affect normal skin.

Does fluorouracil cream enter the bloodstream?

Both studies demonstrated that fluorouracil is minimally absorbed into the systemic circulation.

Fluorouracil Skin Treatment - Before, During, and After

42 related questions found

How long do you leave fluorouracil on?

If you are using fluorouracil to treat actinic or solar keratoses, you should continue using it until the lesions start to peel off. This usually takes about 2 to 4 weeks. However, the lesions may not be completely healed until 1 or 2 months after you stop using fluorouracil.

Does fluorouracil weaken your immune system?

A new study shows two chemotherapy drugs prevalent in the clinic-gemcitabine and 5-fluorouracil-may influence the immune response in a way that facilitates tumor growth.

Will fluorouracil remove age spots?

Fluorouracil is already used as a prescription skin treatment for actinic keratoses, which are precancerous lesions caused by sun damage. Patients getting such treatment have also reported softer, smoother, less wrinkled skin -- and now, a new study confirms those skin improvements.

What do you put on skin after fluorouracil treatment?

The day after your last Efudex application, begin moisturizing all treated areas with either Vaseline or Aquaphor Healing Ointment (over the counter). Apply frequently every day to keep skin soft. The treated area can be pink for several months and is more susceptible to getting sun burned.

What are the benefits of using fluorouracil?

Fluorouracil belongs to the group of medicines known as antimetabolites. When applied to the skin, it is used to treat certain skin problems, including cancer or conditions that could become cancerous if not treated. Fluorouracil interferes with the growth of abnormal cells, which are eventually destroyed.

How do you stop fluorouracil itching?

Over-the-counter Tylenol and Benadryl are helpful for the increasing pain and constant itch. My dermatologist is one who recommends that no other products be applied to the treated areas during treatment other than water and a mild soap or facial cleanser.

What does your skin look like after using fluorouracil cream?

Fluorouracil may cause redness, soreness, scaling, and peeling of affected skin after 1 or 2 weeks of use. This effect may last for several weeks after you stop using the medicine and is to be expected. Sometimes a pink, smooth area is left when the skin treated with this medicine heals.

Does fluorouracil make your hair fall out?

Side Effects

Skin irritation, burning, redness, dryness, pain, swelling, tenderness, or changes in skin color may occur at the site of application. Eye irritation (e.g., stinging, watering), trouble sleeping, irritability, temporary hair loss, or abnormal taste in the mouth may also occur.

Can you shower when using fluorouracil?

Do not use cosmetics or other skin medication on treated areas without first obtaining your doctor's approval. You can get your face wet in the shower. However, it is advisable not to apply immediately before showering.

Does fluorouracil cause scarring?

Common side effects may include: skin pain, itching, burning, or irritation; skin darkening or scarring; skin redness and swelling; or.

What is the erosion stage of fluorouracil treatment?

What is the Efudex erosion stage? Erosion is the end of your Efudex treatment. This is the point at which you and your doctor will together decide to cease application of the chemotherapy cream. Simply put, the cream has done all it can, and it's time to begin healing.

Can you put Vaseline over fluorouracil?

Once you finish the medication, the area of skin treated will be red and raw. It generally takes about 3-4 weeks for all of the inflammation to resolve. You may use Vaseline or Eucerin cream to soothe the skin.

Can I use hydrocortisone with fluorouracil?

You may apply Aquaphor, Vaseline, or over-the-counter Hydrocortisone ointment to the area treated after applying Efudex. Do not apply prior to Efudex application.

Does fluorouracil cause weight gain?

Swelling and redness at the site of the medication injection. Liver damage which may cause yellowing of eyes and skin. Kidney damage which may require dialysis. Weight gain, weight loss, dehydration.

Do you rub in fluorouracil cream?

Fluorouracil cream is applied once or twice a day after washing with plain water. A tiny amount of the cream should be gently rubbed into all of the treatment areas with a fingertip. It is important to apply it to all the skin and not just visible lesions.

How do you know when to stop using efudex cream?

Stop efudix if you experience a severe reaction (shortness of breath; swelling of your lips,face, or tongue; hives). Contact us if you have any problems during treatment. Any lesions that fail to resolve with efudix treatment should be re-examined.

How long do side effects of fluorouracil last?

Most people using this drug get skin reactions where this drug is used. These reactions include burning, dryness, irritation, redness, pain, and swelling. Irritation may last for 2 weeks or longer after you stop using this drug. Call your doctor if you get a skin reaction that bothers you.

Is fluorouracil safe for lips?

Do NOT use Efudex on eyelids or lips unless specifically directed to do so. Care must be taken with Efudex in skin fold areas like the fold from the nose to the corner of the mouth. Try to avoid having any Efudex accumulate in those areas.

Is fluorouracil cream a form of chemotherapy?

FLUOROURACIL, 5-FU (flure oh YOOR a sil) is a chemotherapy agent. It is used on the skin to treat skin cancer and certain types of skin conditions that could become cancer.

How soon can I wash after applying fluorouracil?

Do not wash the face for at least three hours after Efudex (or Carac) application.